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中文名称： NCSTN抗原（重组蛋白）
英文名称： NCSTN Antigen (Recombinant Protein)
别 名： nicastrin; ATAG1874
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
Fusion protein corresponding to a region derived from 34-330 amino acids of human NCSTN
技术规格
|
Full name: |
nicastrin |
|
Synonyms: |
ATAG1874 |
|
Swissprot: |
Q92542 |
|
Gene Accession: |
BC047621 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and beta-amyloid precursor protein, and may be a stabilizing cofactor required for gamma-secretase complex assembly. |
