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中文名称： HMGCL抗原（重组蛋白）
英文名称： HMGCL Antigen (Recombinant Protein)
别 名： HL
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 28-325 amino acids of human HMGCL |
|
Full name: |
3-hydroxymethyl-3-methylglutaryl-CoA lyase |
|
Synonyms: |
HL |
|
Swissprot: |
P35914 |
|
Gene Accession: |
BC010570 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
