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中文名称： GYPC抗原（重组蛋白）
英文名称： GYPC Antigen (Recombinant Protein)
别 名： GE; GPC; GPD; GYPD; CD236; PAS-2; CD236R; PAS-2
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to N terminal 57 amino acids of human GYPC |
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Full name: |
glycophorin C |
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Synonyms: |
GE; GPC; GPD; GYPD; CD236; PAS-2; CD236R; PAS-2 |
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Swissprot: |
P04921 |
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Gene Accession: |
BC104246 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. |
