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Full name: |
zinc finger E-box binding homeobox 2 |
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Synonyms: |
SIP1; SIP-1; ZFHX1B; HSPC082; SMADIP1 |
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Swissprot: |
O60315 |
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Gene Accession: |
BC127102 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene. |
