ST14抗原（重组蛋白）

Full name:

suppression of tumorigenicity 14 (colon carcinoma)

Synonyms:

HAI; MTSP1; SNC19; MT-SP1; PRSS14; TADG15; TMPRSS14

Swissprot:

Q9Y5Y6

Gene Accession:

BC030532

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors.