中文名称: EZR抗原(重组蛋白)
英文名称: EZR Antigen (Recombinant Protein)
别 名: CVL; CVIL; VIL2; HEL-S-105
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
| Fusion protein corresponding to a region derived from 2-295 amino acids of human EZR | 
| Full name: | ezrin | 
| Synonyms: | CVL; CVIL; VIL2; HEL-S-105 | 
| Swissprot: | P15311 | 
| Gene Accession: | BC013903 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. | 
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