中文名称:CBR1抗原(重组蛋白)
英文名称: CBR1 Antigen (Recombinant Protein)
别 名: CBR; hCBR1; SDR21C1
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
Fusion protein corresponding to a region derived from 2-277 amino acids of human CBR1 |
技术规格:
Full name: |
carbonyl reductase 1 |
Synonyms: |
CBR; hCBR1; SDR21C1 |
Swissprot: |
P16152 |
Gene Accession: |
BC002511 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. |