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中文名称： CHMP5抗原（重组蛋白）
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Full name: |
charged multivesicular body protein 5 |
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Synonyms: |
Vps60; CGI-34; PNAS-2; C9orf83; HSPC177; SNF7DC2 |
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Swissprot: |
Q9NZZ3 |
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Gene Accession: |
BC007457 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]). |
