兔抗CYP26B1多克隆抗体

Background:

This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

CYP26B1

Immunogen:

Fusion protein of human CYP26B1

Full name:

cytochrome P450 family 26 subfamily B member 1

Synonyms:

RHFCA; CYP26A2; P450RAI2; P450RAI-2

SwissProt:

Q9NR63

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human brain

IHC Recommend dilution:

20-100