DDOST 抗原（重组蛋白）

Full name:

dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit

Synonyms:

OST; WBP1; AGER1; CDG1R; OST48; OKSWcl45

Swissprot:

P39656

Gene Accession:

BC002594

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.