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中文名称：AREG 抗原（重组蛋白）
英文名称： AREG Antigen (Recombinant Protein)
别 名： amphiregulin; AR; SDGF; CRDGF
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 101-252 amino acids of human AREG |
|
Full name: |
amphiregulin |
|
Synonyms: |
AR; SDGF; CRDGF |
|
Swissprot: |
P15514 |
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Gene Accession: |
BC009799 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype |
