中文名称:ADAMTSL2 抗原(重组蛋白)
英文名称: ADAMTSL2 Antigen (Recombinant Protein)
别 名: ADAMTS-like 2; GPHYSD1
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
| Fusion protein corresponding to C terminal 250 amino acids of human ADAMTSL2 | 
| Full name: | ADAMTS-like 2 | 
| Synonyms: | GPHYSD1 | 
| Swissprot: | Q86TH1 | 
| Gene Accession: | BC050544 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia. | 
		
	
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