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中文名称：ACVR1C 抗原（重组蛋白）
英文名称： ACVR1C Antigen (Recombinant Protein)
别 名： activin A receptor, type IC; ALK7; ACVRLK7
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to a region derived from 195-485 amino acids of human ACVR1C |
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Full name: |
activin A receptor, type IC |
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Synonyms: |
ALK7; ACVRLK7 |
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Swissprot: |
Q8NER5 |
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Gene Accession: |
BC022530 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]). |
