小鼠抗PARVB单克隆抗体

Background:

This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011].

Applications:

WB, IHC, IF

Name of antibody:

PARVB

Immunogen:

Fusion protein of human PARVB

Full name:

parvin, beta (PARVB), transcript variant 2

Synonyms:

CGI-56

SwissProt:

Q9HBI1

IHC positive control:

human liver tissue

IHC Recommend dilution:

30-150

WB Predicted band size:

42 kDa

WB Positive control:

SVT2, A549, PC12 cell lysates

WB Recommended dilution:

500-2000