小鼠抗RFC2单克隆抗体

Background:

The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also called activator 1, is a protein complex consisting of five distinct subunits of 145, 40, 38, 37, and 36.5 kD. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP. Deletion of this gene has been associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].

Applications:

WB, FC

Name of antibody:

RFC2

Immunogen:

Fusion protein of human RFC2

Full name:

replication factor C (activator 1) 2, 40kDa (RFC2), transcript variant 2

Synonyms:

RFC40

SwissProt:

P35250

WB Predicted band size:

39 kDa

WB Positive control:

HepG2, Hela, SVT2, COS7, Jurkat, MDCK cell lysates

WB Recommended dilution:

200-1000