HSPH1抗原（重组蛋白）

Full name:

Heat shock 105kDa/110kDa protein 1

Synonyms:

HSP105; HSP105A; HSP105B; NY-CO-25

Swissprot:

Q92598

Gene Accession:

BC037553

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Heat shock protein 105 kDa is a protein that in humans is encoded by the HSPH1 gene. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells. Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.