小鼠抗PSMA2单克隆抗体

Background:

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. [provided by RefSeq, Jul 2008].

Applications:

WB, IHC

Name of antibody:

PSMA2

Immunogen:

Fusion protein of human PSMA2

Full name:

proteasome (prosome, macropain) subunit, alpha type, 2 (PSMA2)

Synonyms:

HC3; MU; PMSA2; PSC2

SwissProt:

P25787

IHC positive control:

carcinoma of human lung tissue

IHC Recommend dilution:

100-500

WB Predicted band size:

26 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates

WB Recommended dilution:

1000-5000