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021-54845833/15800441009
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Background: |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. [provided by RefSeq, Jul 2008]. |
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Applications: |
WB, IHC |
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Name of antibody: |
PSMA2 |
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Immunogen: |
Fusion protein of human PSMA2 |
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Full name: |
proteasome (prosome, macropain) subunit, alpha type, 2 (PSMA2) |
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Synonyms: |
HC3; MU; PMSA2; PSC2 |
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SwissProt: |
P25787 |
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IHC positive control: |
carcinoma of human lung tissue |
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IHC Recommend dilution: |
100-500 |
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WB Predicted band size: |
26 kDa |
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WB Positive control: |
HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates |
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WB Recommended dilution: |
1000-5000 |
