兔抗LAMA3多克隆抗体

Background:

Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. The protein encoded by this gene is the alpha-3 subunit of laminin 5, which is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Applications:

ELISA, IHC

Name of antibody:

LAMA3

Immunogen:

Synthetic peptide of human LAMA3

Full name:

laminin, alpha 3

Synonyms：

E170, LOCS, BM600, LAMNA, lama4a

SwissProt:

Q16787

ELISA Recommended dilution:

1000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

25-100