兔抗BLM(Phospho-Thr99)多克隆抗体

Background:

The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination.

Applications:

WB, IHC

Name of antibody:

BLM(Phospho-Thr99)

Immunogen:

Peptide sequence around phosphorylation site of threonine 99 (Q-E-T(p)-Q-R) derived from Human Bloom Syndrome.

Full name:

Bloom syndrome, RecQ helicase-like

Synonyms：

BS; RECQ2; RECQL2; RECQL3

SwissProt:

P54132

IHC positive control:

Human heart tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

159 kDa

WB Positive control:

HepG2 cells lysates

WB Recommended dilution:

500-1000