兔抗DCTN3多克隆抗体

Background:

This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

DCTN3

Immunogen:

Fusion protein of human DCTN3

Full name:

dynactin 3 (p22)

Synonyms：

DCTN22; DCTN-22

SwissProt:

O75935

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human thyroid cancer and human cervical cancer

IHC Recommend dilution:

100-300